If you're likely only to be doing mileage this high for a couple of years, provided you keep the car afterwards it makes less of a difference.
Most cars, if properly maintained will last without too much hassle to about 200k miles or 10 years, whichever comes first. The car won't be worth much at 5 years old because of the mileage, but if you've maintained it correctly it should be good for another few years.
I'd second the suggestion of an i30. The long warranty is very useful and when I've had them as hire cars have found the seats pretty comfortable, even in the base model cars. I got about 50mpg on the motorway in the 1.0 Petrol version.
The other option might be to look at leasing, and put the miles on someone else's car. 50k pa isn't that unusual on company cars (sales reps, service engineers etc) and most of those companies use leasing rather than buying the car outright. A quick Google search comes up with a lease costing £300 ish per month for a 3 year lease on a Leon at that mileage.
Final alternative, if you're not bothered about what you're driving and needing the AA from time to time is to buy something for about £1000, run it until it dies, take it to the scrapyard and repeat. How long the car lasts is a fair bit down to luck though. A friend who does massive miles for work took a ten year old Piccasso from 100k miles to nearly 300k miles over 4 years with it only needing routine maintenance, but the next car he bought only lasted a couple of months.
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