How do I replace lost car keys?

I have lost one of my sets of keys for my Ford Focus Estate and need to have them replaced. What's the best way to do this?

Where's the best place to get a keyfob programmed?

I've just bought a Peugeot 207. It only came with one keyfob, which is all falling apart. I can get new keys and fobs but they need programming to the car for the immobiliser. Where is the best place to...